SCHEMBL5121663

SCHEMBL5121663

Nc1ccc(COc2ccc(N)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.80
APP P05067 2/20 0.80
GAA P10253 1/20 0.79
MAPT P10636 1/20 0.79
MAOA P21397 1/20 0.79
RAB9A P51151 1/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
L3MBTL1 Q9Y468 1/20 0.79
F2 P00734 1/20 0.58
PRSS1 P07477 1/20 0.58
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542030 1.00 MAOB (0.80) MAOBAPPGAAMAPTMAOA
SCHEMBL11664961 0.89 MAOB (0.73) MAOBAPPGAAMAPTMAOA
SCHEMBL21221839 0.89 MAOB (0.67) MAOBAPPGAAMAPTMAOA
SCHEMBL8942259 0.89 MAOB (0.70) MAOBAPPGAAMAPTMAOA
SCHEMBL11096427 0.89 MAOB (0.67) MAOBAPPGAAMAPTMAOA
SCHEMBL6291434 0.89 MAOB (0.67) MAOBAPPGAAMAPTMAOA
SCHEMBL1578152 0.89 MAOB (1.00) MAOBAPPGAAMAPTMAOA
SCHEMBL8942088 0.89 MAOB (0.73) MAOBAPPGAAMAPTMAOA
SCHEMBL13766361 0.89 MAOB (0.67) MAOBAPPGAAMAPTMAOA
4-Benzyloxyaniline SCHEMBL171449 0.89 MAOB (1.00) MAOBAPPGAAMAPTMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195928-B1 4,4'-DIISOCYANATO-PHENYL BENZYL ETHER, PROCESS FOR ITS PREPARATION AND ITS USE AS AN ISOCYANATE COMPONENT IN THE PREPARATION OF POLYURETHANES BAYER AG (DE) 1989-10-18 EP claimed
US-11384204-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2022-07-12 US disclosed
US-20210155755-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2021-05-27 US disclosed
US-10947345-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2021-03-16 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20170137667-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2017-05-18 US disclosed
US-20170137667-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2017-05-18 US disclosed
CN-102304226-A Polyazomethine hole transport material and preparation method thereof UNIV JILIN 2012-01-04 CN disclosed
US-7459585-B2 Benzene derivatives and pharmaceutical use thereof AJINOMOTO CO., INC. (JP) 2008-12-02 US disclosed
US-20050165114-A1 Benzene derivatives and pharmaceutical use thereof AJINOMOTO CO. INC (JP) 2005-07-28 US disclosed
US-6703379-B2 ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT, ANTICANCER AGENTS, ANTIARTHRITIC AGENTS AJINOMOTO CO., INC. (JP) 2004-03-09 US disclosed
US-20030166693-A1 Benzene derivatives and pharmaceutical use thereof AJINOMOTO CO., INC (JP) 2003-09-04 US disclosed
US-20010018441-A1 Benzene derivatives and Pharmaceutical use thereof AJINOMOTO CO., INC. (JP) 2001-08-30 US disclosed
EP-1113000-A1 BENZENE DERIVATIVES AND MEDICINAL USE THEREOF Ajinomoto Co., Inc. (JP) 2001-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166693-A1 Benzene derivatives and pharmaceutical use thereof NFKBIA, VCAM1, NFKB1 MAOB 1630/4885APP 1760/4885GAA 2081/4885
US-20050165114-A1 Benzene derivatives and pharmaceutical use thereof NFKBIA, VCAM1, NFKB1 MAOB 1377/4885APP 1548/4885GAA 1930/4885
US-20010018441-A1 Benzene derivatives and Pharmaceutical use thereof NFKBIA, VCAM1, NFKB1 MAOB 1630/4885APP 1760/4885GAA 2081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.