Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560246 | 0.88 | ATM (0.60) | SYKCTSSATMSCN9AAPP | |
| SCHEMBL14290269 | 0.88 | ATM (0.60) | SYKCTSSATMSCN9AAPP | |
| SCHEMBL5399082 | 0.87 | SYK (0.57) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL18575405 | 0.85 | SYK (0.55) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL18598101 | 0.85 | SYK (0.55) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL2449438 | 0.85 | PPARA (0.62) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL357466 | 0.85 | PPARA (0.62) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL273071 | 0.81 | ATM (0.64) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL18407225 | 0.81 | PPARA (0.69) | SYKPPARACTSSKLK7KLK5 | |
| SCHEMBL28671164 | 0.79 | PPARA (0.63) | SYKPPARACTSSKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |
| US-7060845-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | NEOMPS (FR) | 2006-06-13 | — | — | US | disclosed |
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20020143191-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | UREKA SARL (FR) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | SYK 3648/4885PPARA 1008/4885CTSS 284/4885 |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | SYK 3648/4885PPARA 1008/4885CTSS 284/4885 |
| US-20020143191-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ACMSD, PROC | SYK 3200/4885PPARA 1247/4885CTSS 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.