Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 7/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | GIPR | P48546 | 1/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367237 | 0.97 | CXCR4 (0.48) | CXCR4CASP1CASP3CASP4CASP5 | |
| SCHEMBL5384105 | 0.96 | CXCR4 (0.45) | CXCR4CCKBRCTSLCTSSCTSK | |
| SCHEMBL5372281 | 0.95 | CXCR4 (0.45) | CXCR4CASP1CASP3CASP4CASP5 | |
| SCHEMBL5367232 | 0.94 | CXCR4 (0.46) | CXCR4CCKBRCTSLCTSSCTSK | |
| SCHEMBL5372278 | 0.92 | CCKBR (0.43) | CXCR4CCKBRCTSLCTSSCTSK | |
| SCHEMBL5369685 | 0.91 | CXCR4 (0.45) | CXCR4CCKBRCTSLCTSSCTSK | |
| SCHEMBL5367479 | 0.86 | F2 (0.42) | GLP1RGCGRGIPR | |
| SCHEMBL31191396 | 0.86 | CXCR4 (0.50) | CXCR4CASP1CASP3CASP4CASP5 | |
| SCHEMBL29800522 | 0.85 | CXCR4 (0.51) | CXCR4CASP1CASP3CASP4CASP5 | |
| SCHEMBL29904119 | 0.83 | MAGI3 (0.52) | CXCR4CASP1CASP3CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169892-B2 | Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems | ASTELLAS PHARMA INC. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1591450-A1 | CONJUGATE FOR RETENTION IN BLOOD AND CANCER TISSUE-SPECIFIC DRUG DELIVERY | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20050054026-A1 | Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2005-03-10 | — | — | US | disclosed |