Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.74 |
| ▸ | PPARG | P37231 | 7/20 | 0.74 |
| ▸ | PPARD | Q03181 | 7/20 | 0.74 |
| ▸ | PPARA | Q07869 | 7/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | FABP4 | P15090 | 3/20 | 0.74 |
| ▸ | TLR2 | O60603 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL180530 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5808089 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL13571698 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4815941 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL20725794 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL23831109 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Adipic Acid SCHEMBL5664346 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2471966 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL16319776 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9261120 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365172-A | Skin care compositions containing cleansing polymers | 宝洁公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-118984696-A | Kit of cosmetic composition | 布茨公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118541384-A | Novel recombinant collagen polypeptides and molecules | 凯步瑞姆股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| EP-3876901-B1 | LOW SHEAR STRESS CONDITIONER COMPOSITION WITH SPHERICAL GEL NETWORK VESICLES | PROCTER & GAMBLE (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-114096228-B | Skin care composition | 布茨公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117999061-A | Compositions comprising bioactive agents | 布茨公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117916808-A | Method for identifying solvents for extracellular matrix activin | 布茨公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116806142-A | Tetrapeptides and compositions comprising same | 布茨公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116801858-A | Tetrapeptides and compositions comprising same | 布茨公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116744893-A | Tetrapeptides and compositions comprising same | 布茨公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-101312706-A | External preparation for skin | SHISEIDO CO LTD (JP) | 2008-11-26 | — | — | CN | disclosed |
| EP-1955691-A1 | EXTERNAL PREPARATION FOR SKIN | Shiseido Company, Limited (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20050180942-A1 | oil-based clear liquid; becomes neither turbid nor considerably viscous due to emulsification or suspension even when mixed with a significant amount of water | KAO CORPORATION (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1488775-A1 | CLEANSING PREPARATION | Kao Corporation (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-0882442-B1 | Multi-layer lightweight texture composition | SHISEIDO CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6146647-A | A MULTILAYER LIGHTWEIGHT TEXTURE FOR COSMETIC CONSISTS OF A LIQUID PARAFFIN, WATER, HEXYLENE GLYCOL AND A NONIONIC SURFACTANT WHICH IS A POLYOXYETHYLENE GLYCOL MODIFIED WITH ALCOHOL AND/OR ACID OR ADDUCT | SHISEIDO COMPANY, LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0882442-A1 | Multi-layer lightweight texture composition | SHISEIDO COMPANY, LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5258129-A | Polyetherpolysiloxane | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1993-11-02 | — | — | US | disclosed |
| US-4988449-A | SURFACTANTS THAT INCREASE THE FLUID PERMEABILITY TO NONWOVEN SHEETS OF POLYOLEFINS | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4921622-A | Fluid-permeable agent for non-woven sheets of polyolefin fibers and method of application thereof: N,N-di-hydroxyethyl amide and polyoxyalkylene-modified silicone | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1990-05-01 | — | — | US | disclosed |