Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.93 |
| ▸ | TSHR | P16473 | 3/20 | 0.93 |
| ▸ | MEN1 | O00255 | 2/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetyl Alcohol SCHEMBL6869168 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL11019558 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Heptanol SCHEMBL20856916 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL8388758 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL29017475 | 0.97 | LMNA (0.87) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL25421234 | 0.96 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Docosanol SCHEMBL21218972 | 0.96 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Undecanol SCHEMBL17978221 | 0.96 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL20515901 | 0.96 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Heptanol SCHEMBL2685228 | 0.96 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186534-B1 | Potent inhibitors of human 9-cis retinol dehydrogenase | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-06 | — | — | US | disclosed |
| US-6171837-B1 | AMINO ACID AND NUCLEOTIDE SEQUENCE; SCREENING FOR PREDISPOSITION TO CANCER; SCREENING FOR ENZYME INHIBITORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2001-01-09 | — | — | US | disclosed |