SCHEMBL538472

SCHEMBL538472

CCCCCCCCCCCCCCCC1OC1C(=O)OCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
EPHX1 P07099 1/20 0.43
TSHR P16473 3/20 0.42
PPARG P37231 3/20 0.40
HCAR2 Q8TDS4 1/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SPHK2 Q9NRA0 1/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FAAH O00519 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27977118 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL538751 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL27976753 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL1332659 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL11396662 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL28064054 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL538424 0.97 NAAA (0.42) NAAAEPHX1TSHRPPARGALDH1A1
SCHEMBL4732664 0.97 NAAA (0.42) NAAAEPHX1TSHRPPARGALDH1A1
SCHEMBL27976763 0.93 PPM1B (0.43) NAAAEPHX1TSHRSPHK2SPHK1
SCHEMBL11395948 0.91 NAAA (0.39) NAAAEPHX1TSHRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011071674-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-06-16 WO claimed
US-20100113664-A1 Asymmetric Cyclic Diester Compounds FERRO CORPORATION (US) 2010-05-06 US claimed
EP-1921515-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2013-12-04 EP disclosed
EP-1271259-B1 Image forming apparatus and process cartridge therefor RICOH CO LTD (JP) 2013-11-20 EP disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
EP-2146251-B1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH CO LTD (JP) 2012-02-08 EP disclosed
WO-2011071674-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-06-16 WO disclosed
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
EP-1921507-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2011-04-13 EP disclosed
EP-2307476-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-04-13 EP disclosed
US-7729634-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2010-06-01 US disclosed
EP-1403722-B1 Electrophotographic photoconductor, electrophotography method, electrophotographic apparatus, eletrophotographic apparatus process cartridge using a specific outermost surface layer coating solution for the photoconductor RICOH KK (JP) 2005-08-03 EP disclosed
US-6899983-B2 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2005-05-31 US disclosed
US-20050084287-A1 Image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2005-04-21 US disclosed
US-20040126687-A1 Electrophotographic photoconductor, electrophotography method using the same, electrophotographic apparatus, electrophotographic apparatus process cartridge and electrophotographic photoconductor outermost surface layer coating solution RICOH COMPANY, LTD. (JP) 2004-07-01 US disclosed
US-6741821-B2 Image forming apparatus, and process cartridge for use in image forming apparatus RICOH COMPANY, LTD. (JP) 2004-05-25 US disclosed
EP-1403722-A1 Electrophotographic photoconductor, electrophotography method, electrophotographic apparatus, eletrophotographic apparatus process cartridge using a specific outermost surface layer coating solution for the photoconductor Ricoh Company (JP) 2004-03-31 EP disclosed
US-20040048177-A1 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2004-03-11 US disclosed
US-20030035660-A1 Image forming apparatus, and process cartridge for use in image forming apparatus RICOH COMPANY, LTD. (JP) 2003-02-20 US disclosed
EP-1271259-A1 Image forming apparatus and process cartridge therefor Ricoh Company, Ltd. (JP) 2003-01-02 EP disclosed