Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253468 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2887852 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2890583 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL8773435 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2890107 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL339686 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL1692071 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2882451 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2890680 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 | |
| SCHEMBL2889761 | 0.98 | MAOA (0.80) | MAOACHRM2HRH4HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671781-B | Method for converting arylbenzylamine into arylnitrile compound | 南通大学 | 2024-04-19 | — | — | CN | claimed |
| CN-114671781-A | Method for efficiently converting arylbenzylamine into aryl nitrile compound | 南通大学 | 2022-06-28 | — | — | CN | claimed |
| CN-108610338-A | A kind of preparation method of Pyrimidone amide | 天津国际生物医药联合研究院 | 2018-10-02 | — | — | CN | claimed |
| CN-105218391-B | L winestone acid monoester monoamides class compounds | 天津青松华药医药有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-106397100-A | Synthesis method of amorolfine drug intermediate p-tertiary amyl benzyl bromide | 厦门市凯尔利信息科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103459452-B | Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom | EVONIK DEGUSSA GMBH (DE) | 2016-11-30 | — | — | CN | claimed |
| CN-105218391-A | D-tartrate monoesters monoamide compounds | TIANJIN GREENPINE CHINESE MEDICINE PHARMACEUTICAL CO LTD | 2016-01-06 | — | — | CN | claimed |
| CN-105218392-A | L-TARTARIC ACID monoesters monoamide compounds | TIANJIN GREENPINE CHINESE MEDICINE PHARMACEUTICAL CO LTD | 2016-01-06 | — | — | CN | claimed |
| CN-103459452-A | Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom | EVONIK DEGUSSA GMBH | 2013-12-18 | — | — | CN | claimed |
| US-20120248033-A1 | POROUS MATERIALS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF | WATERS TECHNOLOGIES CORPORATION (US) | 2012-10-04 | — | — | US | claimed |
| US-20060155141-A1 | Process for producing benzylamine derivative | ITO AKINORI | 2006-07-13 | — | — | US | claimed |
| US-20060021939-A1 | Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof | WATERS INVESTMENTS LIMITED (US) | 2006-02-02 | — | — | US | claimed |
| EP-1586552-A1 | PROCESS FOR PRODUCING BENZYLAMINE DERIVATIVE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-10-19 | — | — | EP | claimed |
| CN-1063429-C | Preparation of arylbenzylamines | BASF AG (DE) | 2001-03-21 | — | — | CN | claimed |
| US-5840977-A | CYCLOHEXANOL UREA DERIVATIVE AS INTERMEDIATE | FUJIREBIO INC. (JP) | 1998-11-24 | — | — | US | claimed |
| CN-1115754-A | Preparation of arylbenzylamines | BASF AG (DE) | 1996-01-31 | — | — | CN | claimed |
| EP-0612740-A1 | Methods of producing pantothenic acid derivative and its starting materials for producing the same | FUJIREBIO Inc. (JP) | 1994-08-31 | — | — | EP | claimed |
| US-5264583-A | Photographic coupler and method of making the same | EASTMAN KODAK COMPANY (US) | 1993-11-23 | — | — | US | claimed |
| EP-0018415-B1 | PROCESS FOR PRODUCING ALKYL 4-(ALKOXY METHYL PHOSPHINOYL)BUTYRATES AND ALKYL-(2-AMINO-4-(ALKOXY METHYL PHOSPHINOYL)) BUTYRATES | MEIJI SEIKA KAISHA LTD. (JP) | 1982-10-13 | — | — | EP | claimed |
| EP-0018415-A1 | Process for producing alkyl 4-(alkoxy methyl phosphinoyl)butyrates and alkyl-(2-amino-4-(alkoxy methyl phosphinoyl)) butyrates | MEIJI SEIKA KAISHA LTD. (JP) | 1980-11-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155141-A1 | Process for producing benzylamine derivative | BRD7, BRD1, BRD2 | MAOA 1051/4885CHRM2 143/4885HRH4 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.