Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572320 | 0.98 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL573476 | 0.95 | EPHX1 (0.33) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8958541 | 0.95 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8958407 | 0.95 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23870287 | 0.95 | EPHX1 (0.31) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19280369 | 0.91 | EPHX1 (0.31) | LMNA | |
| SCHEMBL4196047 | 0.85 | — | — | |
| SCHEMBL3121565 | 0.82 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28425490 | 0.78 | MME (0.33) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14212132 | 0.77 | EPHX1 (0.31) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994109-A | Preparation method of lysine-specific demethylase 1 inhibitor | 成都苑东生物制药股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-116463159-B | Antioxidant additive, preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-117720521-A | Salt of nitrogen-containing heterocyclic ketone compound and preparation method thereof | 江苏豪森药业集团有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117447461-A | Preparation method of pyrazoloheteroaryl derivative | 苏州盛迪亚生物医药有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116463159-A | Antioxidant additive, preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-111320542-B | Antioxidant containing double hindered phenol structures and preparation method thereof | 中国石油天然气股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-112552299-B | Preparation method of linagliptin for treating type II diabetes | 山东罗欣药业集团恒欣药业有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-111138413-B | Preparation method of cyclin-dependent kinase inhibitor and intermediate thereof | 江苏豪森药业集团有限公司 | 2022-11-04 | — | — | CN | claimed |
| US-11299455-B2 | Process for diastereoselective synthesis of vicinal diamines | PIRAMAL PHARMA LIMITED (IN) | 2022-04-12 | — | — | US | claimed |
| US-20220073454-A1 | AN IMPROVED PROCESS FOR DIASTEREOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | PIRAMAL PHARMA LIMITED (IN) | 2022-03-10 | — | — | US | claimed |
| EP-0521686-A1 | Stereoselective production of hydroxyamide compounds from chiral a-amino epoxides | MERCK & CO. INC. (US) | 1993-01-07 | — | — | EP | claimed |
| US-5169952-A | Addition of metalated amide enolates to chiral alpha amino metalated epoxides | MERCK & CO., INC. (US) | 1992-12-08 | — | — | US | claimed |
| US-RE33495-E | Stereoselective preparation of 3-substituted-4-anilino-piperidine compounds and derivatives | BOC, INC. (US) | 1990-12-18 | — | — | US | claimed |
| EP-0389551-A1 | STEREOSELECTIVE PREPARATION OF 3-SUBSTITUTED-4-(PHENYL ANILO) PIPERIDINE COMPOUNDS AND DERIVATIVES | BOC, INC. (US) | 1990-10-03 | — | — | EP | claimed |
| US-4849521-A | DEPROTONATION, ALKYLATION, REDUCTION | BOC, INC. (US) | 1989-07-18 | — | — | US | claimed |
| WO-1989004300-A1 | STEREOSELECTIVE PREPARATION OF 3-SUBSTITUTED-4-(PHENYL ANILO) PIPERIDINE COMPOUNDS AND DERIVATIVES | BOC, INC. (US) | 1989-05-18 | — | — | WO | claimed |
| EP-0127429-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE ((3-AMINO-3-CARBOXY)PROPYL-1) PHOSPHINIC ACID DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1989-04-19 | — | — | EP | claimed |
| US-4515950-A | Process for the isomerization of ergovine derivatives | SANDOZ LTD. (CH) | 1985-05-07 | — | — | US | claimed |
| US-4499027-A | REACTING A SHIFF'S BASE AND AN ALKYL VINYL PHOSPHINATE USING A BASIC CATALYST; HYDROLYSIS; STEREOSPECIFIC | MEIJI SEIKA KAISHA, LTD. (JP) | 1985-02-12 | — | — | US | claimed |
| EP-0127429-A2 | Process for preparing optically active ((3-amino-3-carboxy)propyl-1) phosphinic acid derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1984-12-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073454-A1 | AN IMPROVED PROCESS FOR DIASTEREOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | AZI2, SAT1, TET2 | ALDH1A1 1015/4885SMN1; SMN2 1677/4885LMNA 3977/4885 |
| US-11299455-B2 | Process for diastereoselective synthesis of vicinal diamines | AZI2, SAT1, DNMT1 | ALDH1A1 832/4885SMN1; SMN2 2248/4885LMNA 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.