Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 9/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400052 | 0.80 | MAP2K2 (0.50) | ANPEPMAP2K2MAP2K1BACE1LMNA | |
| SCHEMBL13301431 | 0.80 | ANPEP (0.46) | ANPEPMAP2K2MAP2K1BACE1CNR2 | |
| SCHEMBL302722 | 0.76 | ALDH1A1 (0.52) | CYP3A4CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL9770073 | 0.76 | BACE1 (0.56) | ANPEPMAP2K2MAP2K1BACE1CNR2 | |
| SCHEMBL29738643 | 0.76 | BACE1 (0.56) | ANPEPMAP2K2MAP2K1BACE1CNR2 | |
| SCHEMBL28251159 | 0.76 | ANPEP (0.53) | ANPEPMAP2K2MAP2K1BACE1CNR2 | |
| SCHEMBL5215555 | 0.73 | ALDH1A1 (0.46) | LMNAALDH1A1POLB | |
| SCHEMBL6493935 | 0.72 | CYP2A6 (0.50) | ANPEPMAP2K2MAP2K1BACE1CNR2 | |
| SCHEMBL4710954 | 0.72 | ANPEP (0.42) | ANPEPMAP2K2MAP2K1LMNACYP3A4 | |
| SCHEMBL5282055 | 0.72 | CYP2A6 (0.50) | ANPEPMAP2K2MAP2K1BACE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39590-E1 | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | ISK AMERICAS INCORPORATED (US) | 2007-04-24 | — | — | US | disclosed |
| US-6545161-B2 | Potato and corn crops | ISK AMERICAS INCORPORATED | 2003-04-08 | — | — | US | disclosed |