Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960774 | 0.98 | MAPT (0.64) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL538564 | 0.96 | MAPT (0.62) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL14288507 | 0.95 | MAPT (0.72) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL18015983 | 0.94 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7619627 | 0.94 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL538924 | 0.94 | MAPT (0.74) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL918880 | 0.94 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL31003494 | 0.94 | MAPT (0.74) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9239597 | 0.93 | MAPT (0.61) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9710106 | 0.93 | MAPT (0.61) | MAPTKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029504-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140046022-A1 | FLUORENE COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8569453-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2415744-A1 | FLUORENE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100240867-A1 | FLUORENE COMPOUND | AJINOMOTO CO. INC. (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046022-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | MAPT 656/4885KMT2A 2658/4885MEN1 115/4885 |
| US-20100240867-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | MAPT 656/4885KMT2A 2658/4885MEN1 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.