Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.69 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.69 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710702 | 0.91 | CHRM1 (0.78) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL6600748 | 0.90 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL5386373 | 0.90 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL5386370 | 0.90 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| Hydrochloric Acid SCHEMBL5482985 | 0.90 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| Hydrochloric Acid SCHEMBL5379970 | 0.89 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| Hydrochloric Acid SCHEMBL5388919 | 0.89 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL4403937 | 0.86 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL44492 | 0.85 | CHRM1 (0.63) | CHRM1CHRM2CHRM4CHRM3SLC18A3 | |
| SCHEMBL29467164 | 0.85 | CHRM1 (0.63) | CHRM1CHRM2CHRM4CHRM3SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7164024-B2 | Muscarinic acetylcholine receptor antagonist; Parkinson's disease; dystonia; analgesics; irritable bowel syndrome | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1386920-A1 | BENZIMIDAZOLONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-02-04 | — | — | EP | disclosed |