Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butyl Hydroperoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Hydroperoxide SCHEMBL2671237 | 1.00 | ALDH1A1 (0.69) | ALDH1A1TSHRCA1CA2CA9 | |
| Tert-Butyl Hydroperoxide SCHEMBL27609021 | 1.00 | ALDH1A1 (0.69) | ALDH1A1TSHRCA1CA2CA9 | |
| Tert-Butyl Hydroperoxide SCHEMBL28376532 | 0.96 | ALDH1A1 (0.64) | ALDH1A1TSHRCA1CA2CA9 | |
| Cyclohexane SCHEMBL16197528 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TSHRCA1CA2CA9 | |
| Cyclohexane SCHEMBL10008939 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TSHRCA1CA2CA9 | |
| Tert-Butyl Hydroperoxide SCHEMBL2586869 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TSHRCA1CA2CA9 | |
| Tert-Butyl Hydroperoxide SCHEMBL1203656 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRDGAT1HMGCRCHRM1 | |
| Tert-Butyl Hydroperoxide SCHEMBL3309161 | 0.88 | — | — | |
| Pivalate SCHEMBL27462861 | 0.86 | ALDH1A1 (0.60) | ALDH1A1TSHRDGAT1HMGCRCHRM1 | |
| Tert-Butyl Hydroperoxide SCHEMBL28766180 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504519-A | Sulfonate type fluoro surfactant with degradability and excellent emulsifying property and preparation method thereof | 卫星化学股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-110088388-B | Liquid composition comprising two initiators, method for polymerization thereof, use and material or composition obtained after polymerization of the composition | 阿肯马法国公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115782312-A | Three-layer coating pipe and preparation method thereof | 苏州兆管鑫塑料科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115386185-A | Swelling insulation coating film for lithium battery and preparation method thereof | 芜湖徽氏新材料科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115343215-A | Evaluation method for precipitation performance of different additives in POE (polyolefin elastomer) adhesive film | 宿迁威科新材料有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-112920722-B | Water-blocking packaging adhesive film and preparation method thereof | 苏州赛伍应用技术股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115287003-A | Composite hot melt adhesive film for metal bonding and preparation method thereof | 广东汇齐新材料有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-112159500-B | Anti-mud polycarboxylic acid high-performance water reducing agent and preparation method and application thereof | 中国建筑股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-112126021-B | Mud-resistant polycarboxylic acid water reducer and preparation method thereof | 中国建筑股份有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-110041470-B | Functionalized olefin block copolymer antioxidant masterbatch and preparation method thereof | 佳易容相容剂江苏有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-112898470-A | High-cohesiveness fluorine-containing polymer, preparation method thereof and coating | 武汉飞腾亚化工新材料有限公司 | 2021-06-04 | — | — | CN | claimed |
| US-10961438-B2 | Method for reducing the viscosity of viscosified fluids for applications in natural gas and oil fields | TOUGAS OILFIELD SOLUTIONS GMBH (DE) | 2021-03-30 | — | — | US | claimed |
| CN-108948689-B | Polylactic acid-lignin composite material modified by reactive extrusion method and preparation method thereof | 济宁明升新材料有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-108948690-B | Polylactic acid-lignin-starch composite material and preparation method thereof | 济宁明升新材料有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-111681877-A | Ionic liquid electrolyte for ultra-high stability aluminum electrolytic capacitor and preparation method thereof | 上海交通大学 | 2020-09-18 | — | — | CN | claimed |
| CN-111333780-A | Preparation method of polyolefin graft | 上海康谐塑业有限公司 | 2020-06-26 | — | — | CN | claimed |
| WO-2019200839-A1 | TOUGHENING AGENT FOR HIGH-PERFORMANCE POLYESTER AND ALLOY THEREOF, AND PREPARATION METHOD THEREFOR | 佳易容相容剂江苏有限公司 | 2019-10-24 | — | — | WO | claimed |
| US-20180327655-A1 | METHOD FOR REDUCING THE VISCOSITY OF VISCOSIFIED FLUIDS FOR APPLICATIONS IN NATURAL GAS AND OIL FIELDS | TOUGAS HOLDING GMBH (DE) | 2018-11-15 | — | — | US | claimed |
| WO-2016102126-A1 | METHOD FOR REDUCING THE VISCOSITY OF VISCOSIFIED FLUIDS FOR APPLICATIONS IN NATURAL GAS AND OIL FIELDS | TOUGAS OILFIELD SOLUTIONS GMBH (DE) | 2016-06-30 | — | — | WO | claimed |
| US-6900267-B2 | Methods of CO2-assisted reactive extrusion | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-05-31 | — | — | US | claimed |