Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929611 | 0.84 | EPAS1 (0.45) | PTGS2PTGS1BRD4SMN1; SMN2EPAS1 | |
| SCHEMBL3936441 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2PTGDR2LMNA | |
| SCHEMBL5387735 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1BRD4SMN1; SMN2PTGDR2 | |
| SCHEMBL5397099 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1BRD4SMN1; SMN2PTGDR2 | |
| SCHEMBL3930206 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1SMN1; SMN2LMNAEPAS1 | |
| SCHEMBL1333614 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1SMN1; SMN2PTGDR2LMNA | |
| SCHEMBL1331609 | 0.77 | PTGDR2 (0.62) | SMN1; SMN2PTGDR2GLA | |
| SCHEMBL11192788 | 0.77 | CHRM1 (0.56) | LMNAMAPT | |
| SCHEMBL5397109 | 0.76 | TTR (0.50) | PTGS2PTGS1SMN1; SMN2PTGDR2LMNA | |
| SCHEMBL2395063 | 0.74 | PTGS2 (0.44) | PTGS2PTGS1BRD4EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007502806-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | claimed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |