SCHEMBL5388253

SCHEMBL5388253

C=CCOC(=O)/C=C/C(=O)OCC=C.C=Cc1ccccc1C=C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.53
MAPT P10636 5/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
APP P05067 1/20 0.49
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.43
HCAR2 Q8TDS4 2/20 0.42
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RHOA P61586 1/20 0.40
CASP1 P29466 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5388256 1.00 CYP3A4 (0.53) CYP3A4MAPTCACNA1BAPBA1APP
SCHEMBL3680375 0.89 CYP3A4 (0.53) CYP3A4MAPTCACNA1BAPBA1APP
Styrene SCHEMBL11873129 0.84 CYP3A4 (0.51) CYP3A4MAPTCACNA1BAPBA1APP
Styrene SCHEMBL11873141 0.84 CYP3A4 (0.51) CYP3A4MAPTCACNA1BAPBA1APP
Toluene SCHEMBL11320560 0.81 CYP3A4 (0.51) CYP3A4MAPTCACNA1BAPBA1APP
Toluene SCHEMBL11320582 0.81 CYP3A4 (0.51) CYP3A4MAPTCACNA1BAPBA1APP
SCHEMBL1696561 0.81 CYP3A4 (0.83) CYP3A4MAPTALDH1A1HSD17B10TSHR
SCHEMBL11496920 0.81 CYP3A4 (0.83) CYP3A4MAPTCACNA1BAPBA1APP
Phthalic Acid SCHEMBL5363486 0.81 CYP3A4 (0.61) CYP3A4MAPTCACNA1BAPBA1APP
SCHEMBL10839688 0.81 CYP3A4 (0.83) CYP3A4MAPTCACNA1BAPBA1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5442012-A Process for making encapsulated micro-agglomerated core/shell additives for PVC blends ROHM AND HAAS COMPANY (US) 1995-08-15 US claimed
US-5221713-A CO-MICROAGGLOMERATION OF EMULSION POLYMERS (ENCAPSULATED CORE/SHELL ADDITIVES FOR PVC) ROHM AND HAAS COMPANY (US) 1993-06-22 US claimed
US-7217747-B2 Plastics additives composition, process, and blends thereof ROHM AND HAAS COMPANY (US) 2007-05-15 US disclosed
EP-1111001-B1 Plastics additives composition, process and blends thereof ROHM & HAAS (US) 2006-06-14 EP disclosed
EP-1153936-B1 Plastics additives, improved process, products, and articles containing same ROHM & HAAS (US) 2004-08-04 EP disclosed
US-20040077756-A1 Plastics additives composition, process, and blends thereof WEIER JANE ELIZABETH (US) 2004-04-22 US disclosed
US-6624212-B2 For imparting impact strength and processability to thermoplastic resins ROHM AND HAAS COMPANY 2003-09-23 US disclosed
US-20020013387-A1 For imparting impact strength and processability to thermoplastic resins ROHM AND HAAS COMPANY 2002-01-31 US disclosed
US-20010056150-A1 Plastics additives: improved process, products, and articles containing same SMITH ROBERT JULIAN (US) 2001-12-27 US disclosed
EP-1153936-A2 Plastics additives, improved process, products, and articles containing same ROHM AND HAAS COMPANY (US) 2001-11-14 EP disclosed
EP-1111001-A2 Plastics additives composition, process and blends thereof ROHM AND HAAS COMPANY (US) 2001-06-27 EP disclosed
US-5442012-A Process for making encapsulated micro-agglomerated core/shell additives for PVC blends ROHM AND HAAS COMPANY (US) 1995-08-15 US disclosed
US-5276092-A Encapsulated micro-agglomerated core/shell additives in poly(vinyl chloride) blends ROHM AND HAAS COMPANY (US) 1994-01-04 US disclosed
US-5221713-A CO-MICROAGGLOMERATION OF EMULSION POLYMERS (ENCAPSULATED CORE/SHELL ADDITIVES FOR PVC) ROHM AND HAAS COMPANY (US) 1993-06-22 US disclosed
EP-0536935-A1 Co-microagglomeration of emulsion polymers ROHM AND HAAS COMPANY (US) 1993-04-14 EP disclosed