Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.66 |
| ▸ | ITGA4 | P13612 | 19/20 | 0.66 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388685 | 0.87 | ITGB1 (0.61) | ITGB1ITGA4FPR2ITGA2ITGB7 | |
| SCHEMBL5409081 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5259894 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5258820 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5258825 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5405493 | 0.78 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5260018 | 0.78 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5261152 | 0.77 | ITGB1 (0.65) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5261146 | 0.77 | ITGB1 (0.65) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5261197 | 0.77 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253171-B2 | Urea derivatives as integrin α4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-08-07 | — | — | US | disclosed |