Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 15/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385935 | 0.95 | BDKRB1 (0.49) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5383446 | 0.93 | BDKRB1 (0.50) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5382691 | 0.88 | BDKRB1 (0.49) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5383453 | 0.88 | BDKRB1 (0.51) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5382063 | 0.88 | BDKRB1 (0.49) | BDKRB1NISCHHDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL5377539 | 0.88 | BDKRB1 (0.53) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5393536 | 0.88 | BDKRB1 (0.48) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5385453 | 0.88 | BDKRB1 (0.52) | BDKRB1NISCH | |
| Trifluoroacetic Acid SCHEMBL5402587 | 0.88 | BDKRB1 (0.48) | BDKRB1NISCHHDAC3HDAC4HDAC1 | |
| SCHEMBL5377080 | 0.87 | BDKRB1 (0.53) | BDKRB1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291642-B2 | Bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-20060100219-A1 | Novel bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100219-A1 | Novel bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BDKRB1, BDKRB2, MRGPRX1 | BDKRB1 1/4885NISCH 380/4885CYP4F2 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.