Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 15/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029347 | 0.88 | PPARG (0.73) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL3029685 | 0.81 | PPARG (0.78) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL13940270 | 0.80 | PPARG (0.80) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL5660150 | 0.80 | PPARG (0.80) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL3033927 | 0.79 | HTR6 (0.71) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL3029876 | 0.78 | PPARG (0.75) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL5662529 | 0.76 | HTR6 (0.61) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL352067 | 0.75 | HTR6 (0.51) | PPARGPPARDPPARAHTR6FFAR1 | |
| SCHEMBL3029476 | 0.75 | PPARG (0.75) | PPARGPPARDPPARAHTR6DRD2 | |
| SCHEMBL4815832 | 0.73 | HTR6 (0.75) | PPARGPPARDPPARAHTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202266-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2007-04-10 | — | — | US | claimed |