Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 8/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387868 | 0.90 | HCRTR1 (0.37) | OPRM1OPRK1BDKRB1HRH3PAX8 | |
| SCHEMBL5381807 | 0.89 | NPC1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL5389019 | 0.87 | BDKRB1 (0.36) | OPRM1OPRK1BDKRB1STSMAPT | |
| SCHEMBL5381885 | 0.85 | BDKRB1 (0.36) | OPRM1OPRK1BDKRB1STSMAPT | |
| SCHEMBL5393649 | 0.83 | BDKRB1 (0.44) | BDKRB1STSMAPT | |
| SCHEMBL5392287 | 0.82 | BDKRB1 (0.44) | BDKRB1STS | |
| SCHEMBL5377549 | 0.82 | BDKRB1 (0.39) | BDKRB1STSMAPTHRH3 | |
| SCHEMBL5377425 | 0.81 | SMN1; SMN2 (0.40) | MAPTALDH1A1LMNATSHR | |
| SCHEMBL5402637 | 0.80 | BDKRB1 (0.38) | BDKRB1STS | |
| SCHEMBL5387874 | 0.76 | HCRTR1 (0.36) | OPRM1OPRK1BDKRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291642-B2 | Bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-20060100219-A1 | Novel bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100219-A1 | Novel bradykinin-B1 antagonists, process for their preparation and their use as medicaments | BDKRB1, BDKRB2, MRGPRX1 | OPRM1 372/4885OPRK1 148/4885BDKRB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.