Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399635 | 0.88 | TDP1 (0.57) | TDP1L3MBTL1TSHRKDM4ELMNA | |
| SCHEMBL9251907 | 0.86 | TDP1 (0.59) | TDP1L3MBTL1TSHRKDM4ELMNA | |
| SCHEMBL11670237 | 0.81 | TSHR (0.60) | TDP1L3MBTL1TSHRLMNAMAPK1 | |
| SCHEMBL304456 | 0.80 | TDP1 (0.66) | TDP1L3MBTL1TSHRKDM4ECDC25B | |
| SCHEMBL29351965 | 0.80 | TDP1 (0.66) | TDP1L3MBTL1TSHRKDM4ECDC25B | |
| SCHEMBL15869336 | 0.80 | TDP1 (0.66) | TDP1L3MBTL1TSHRKDM4ECDC25B | |
| Aniline SCHEMBL28224929 | 0.79 | MAPK1 (0.55) | TDP1TSHRKDM4ELMNAMAPK1 | |
| SCHEMBL282685 | 0.79 | TDP1 (0.60) | TDP1L3MBTL1TSHRKDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL5572312 | 0.78 | TDP1 (0.64) | TDP1L3MBTL1TSHRKDM4ECDC25B | |
| Ammonia Solution, Strong SCHEMBL5572316 | 0.78 | TDP1 (0.64) | TDP1L3MBTL1TSHRKDM4ECDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | claimed |