Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307875 | 0.89 | TSHR (0.58) | TDP1L3MBTL1AKR1C3TSHRCDC25B | |
| SCHEMBL5389537 | 0.88 | TDP1 (0.51) | TDP1L3MBTL1AKR1C3TSHRCDC25B | |
| SCHEMBL9251907 | 0.88 | TDP1 (0.59) | TDP1L3MBTL1AKR1C3TSHRCDC25B | |
| SCHEMBL27339443 | 0.88 | TDP1 (0.50) | TDP1L3MBTL1AKR1C3TSHRCDC25B | |
| SCHEMBL8403769 | 0.88 | VCAM1 (0.49) | TDP1L3MBTL1AKR1C3TSHRCDC25B | |
| SCHEMBL411359 | 0.84 | ALDH1A1 (0.59) | TDP1AKR1C3TSHRCDC25BKDM4E | |
| SCHEMBL29351965 | 0.84 | TDP1 (0.66) | TDP1L3MBTL1TSHRCDC25BKDM4E | |
| SCHEMBL27637513 | 0.84 | ALDH1A1 (0.59) | TDP1AKR1C3TSHRCDC25BKDM4E | |
| SCHEMBL15869336 | 0.84 | TDP1 (0.66) | TDP1L3MBTL1TSHRCDC25BKDM4E | |
| SCHEMBL304456 | 0.84 | TDP1 (0.66) | TDP1L3MBTL1TSHRCDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110330465-A | Hydrazone amide derivatives and its application in preparation prevention and treatment alopecia agent | 深圳市三启药物开发有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-110229118-A | Hydrazone amide derivatives and its preparing the application in osteosporosis resistant medicament | 深圳市三启药物开发有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| US-4065477-A | Process for preparing highly pure 1-nitroanthraquinone | BISON-WERKE BAHRE & GRETEN GMBH & CO. KG (US) | 1977-12-27 | — | — | US | claimed |
| CN-110330465-A | Hydrazone amide derivatives and its application in preparation prevention and treatment alopecia agent | 深圳市三启药物开发有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110229118-A | Hydrazone amide derivatives and its preparing the application in osteosporosis resistant medicament | 深圳市三启药物开发有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-101316853-A | Benzothiazole and thiazolopyridine as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-101282974-A | Benzimidazole derivatives as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-101282761-A | Benzimidazole derivatives as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-101277965-A | Imidazo [2, 1-b ] thiazole derivatives as SIRTUIN modulating compounds | SIRTRIS PHARMACEUTICALS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1882307-A | Method for dyeing fibres containing keratine | HENKEL KGAA (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1761517-A | Mixing device | HENKEL KGAA (DE) | 2006-04-19 | — | — | CN | disclosed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | disclosed |
| US-5919933-A | PHOTOSTABILITY, OXIDATION RESISTANCE, RADIATION RESISTANCE, HEAT RESISTANCE | CLARIANT GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| CN-1173493-A | Novel light stabilizers based on sterically hindered amines | HOECHST AG (DE) | 1998-02-18 | — | — | CN | disclosed |
| US-4185024-A | Nitric acid process for the manufacture of anthraquinone from o-benzyl-toluene | BERGWERKSVERBAND GMBH (DE) | 1980-01-22 | — | — | US | disclosed |
| US-4153632-A | 2-Methyl-3-nitrobenzophenone | AMERICAN CYANAMID COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4065477-A | Process for preparing highly pure 1-nitroanthraquinone | BISON-WERKE BAHRE & GRETEN GMBH & CO. KG (US) | 1977-12-27 | — | — | US | disclosed |