Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539346 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL270558 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL3151151 | 0.78 | TSHR (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL8374924 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL11003491 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL17275109 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL17473973 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL2427168 | 0.73 | TSHR (0.37) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL27052120 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL3373685 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414431-A1 | THINNERS FOR AQUEOUS SUSPENSIONS OF MINERAL PARTICLES AND HYDRAULIC BINDER PASTES | Chryso (FR) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112775-A1 | THINNERS FOR AQUEOUS SUSPENSIONS OF MINERAL PARTICLES AND HYDRAULIC BINDER PASTES | CHRYSO (FR) | 2010-10-07 | — | — | WO | disclosed |