SCHEMBL539232

SCHEMBL539232

CNC1CNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20912653 0.97
Hydrochloric Acid SCHEMBL7011143 0.97
SCHEMBL20281600 0.87
Sulfuric Acid SCHEMBL30918631 0.84 CHRNB2 (0.34)
SCHEMBL14444156 0.79
SCHEMBL23746975 0.78
SCHEMBL23080839 0.78
SCHEMBL23746974 0.78
SCHEMBL18968302 0.78
SCHEMBL14504591 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
CN-111819176-B 4-azaindole compounds 百时美施贵宝公司 2023-12-15 CN claimed
CN-111465602-B Synthesis of 4-aminopyrimidine compounds 帕劳制药有限公司 2023-05-23 CN claimed
EP-3697776-B1 SYNTHESIS OF 4-AMINOPYRIMIDINE COMPOUNDS PALAU PHARMA S L U (ES) 2023-04-19 EP claimed
US-11180480-B2 Synthesis of 4-aminopyrimidine compounds SENSORION (FR) 2021-11-23 US claimed
US-20200270228-A1 SYNTHESIS OF 4-AMINOPYRIMIDINE COMPOUNDS SENSORION (FR) 2020-08-27 US claimed
EP-3697776-A1 SYNTHESIS OF 4-AMINOPYRIMIDINE COMPOUNDS Sensorion (FR) 2020-08-26 EP claimed
CN-111465602-A Synthesis of 4-aminopyrimidine compounds 森索睿翁公司 2020-07-28 CN claimed
WO-2019076974-A1 SYNTHESIS OF 4-AMINOPYRIMIDINE COMPOUNDS SENSORION (FR) 2019-04-25 WO claimed
CN-107050030-A Selective histamine H 4 receptor antagonist for treating vestibular disorder 国立健康与医学研究所 2017-08-18 CN claimed
WO-2015106012-A1 AZAINDOLE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-07-16 WO claimed
US-20150191465-A1 AZAINDOLE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-07-09 US claimed
WO-2013130660-A1 AMIDES AS PIM INHIBITORS AMGEN INC. (US) 2013-09-06 WO claimed
US-8202876-B2 Compounds and compositions as protein kinase inhibitors IRM LLC (BM) 2012-06-19 US claimed
US-20100029605-A1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS IRM LLC (BM) 2010-02-04 US claimed
US-20100016293-A1 Quinazolines and Related Heterocyclic Compounds, and Their Therapeutic Use VERENIGING VOOR CHRISTELIJK, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG (NL) 2010-01-21 US claimed
EP-2057146-A1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS IRM LLC (BM) 2009-05-13 EP claimed
EP-2044027-A2 FUSED BICYCLIC COMPOUNDS INTERACTING WITH THE HISTAMINE H4 RECEPTOR Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg (NL) 2009-04-08 EP claimed
WO-2008042639-A1 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS IRM LLC (BM) 2008-04-10 WO claimed
WO-2008003702-A2 FUSED BICYCLIC COMPOUNDS INTERACTING WITH THE HISTAMINE H4 RECEPTOR VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG (NL) 2008-01-10 WO claimed