Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384090 | 0.93 | F10 (0.71) | F10KCNH2NR3C1 | |
| SCHEMBL6107926 | 0.88 | F10 (0.62) | F10KCNH2NR3C1 | |
| SCHEMBL6108664 | 0.87 | F10 (0.63) | F10KCNH2NR3C1 | |
| Hydrochloric Acid SCHEMBL6106871 | 0.87 | F10 (0.72) | F10KCNH2 | |
| SCHEMBL6109232 | 0.86 | F10 (0.62) | F10KCNH2NR3C1 | |
| SCHEMBL6107782 | 0.86 | F10 (0.62) | F10KCNH2NR3C1 | |
| SCHEMBL5389634 | 0.86 | F10 (0.69) | F10KCNH2 | |
| SCHEMBL6107829 | 0.86 | F10 (0.61) | F10KCNH2NR3C1 | |
| Hydrochloric Acid SCHEMBL6105945 | 0.86 | F10 (0.70) | F10KCNH2 | |
| SCHEMBL6108996 | 0.85 | F10 (0.61) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163938-B2 | Substituted carboxamides | ELI LILLY AND COMPANY (US) | 2007-01-16 | — | — | US | disclosed |
| US-20040058959-A1 | Substituted carboxamides | HERRON DAVID KENT (US) | 2004-03-25 | — | — | US | disclosed |
| EP-1379506-A2 | SUBSTITUTED CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002064567-A2 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058959-A1 | Substituted carboxamides | F11, F12, TFPI | F10 16/4885KCNH2 2069/4885NR3C1 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.