Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112857 | 0.85 | LGALS3 (0.40) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5399353 | 0.84 | LGALS3 (0.40) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5482774 | 0.83 | CA1 (0.42) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5398983 | 0.82 | LGALS3 (0.53) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5436171 | 0.82 | LGALS3 (0.39) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5495152 | 0.81 | LGALS3 (0.55) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5389956 | 0.81 | LGALS3 (0.40) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5389972 | 0.81 | LGALS3 (0.47) | LGALS3LGALS1LGALS7; LGALS7BLGALS9 | |
| SCHEMBL5391745 | 0.81 | LGALS3 (0.55) | CA1CA2CA9LGALS3LGALS1 | |
| SCHEMBL5404178 | 0.80 | LGALS3 (0.58) | CA1CA2CA9LGALS3LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2919802-A1 | METHODS, COMPOSITIONS AND KITS FOR TREATING, MODULATING, OR PREVENTING OCULAR ANGIOGENESIS OR FIBROSIS IN A SUBJECT USING A GALECTIN PROTEIN INHIBITOR | Tufts University (US) | 2015-09-23 | — | — | EP | claimed |
| WO-2014078655-A1 | METHODS, COMPOSITIONS AND KITS FOR TREATING, MODULATING, OR PREVENTING OCULAR ANGIOGENESIS OR FIBROSIS IN A SUBJECT USING A GALECTIN PROTEIN INHIBITOR | TUFTS UNIVERSITY (US) | 2014-05-22 | — | — | WO | claimed |
| JP-2007508328-A | — | — | 2007-04-05 | — | — | JP | claimed |
| EP-1682159-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | Ralph, John Stephen (AU) | 2006-07-26 | — | — | EP | claimed |
| WO-2005037293-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | UNIV MONASH (AU) | 2005-04-28 | — | — | WO | claimed |
| EP-1682159-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | Ralph, John Stephen (AU) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005037293-A1 | IMMUNOMODULATING COMPOSITIONS AND USES THEREFOR | UNIV MONASH (AU) | 2005-04-28 | — | — | WO | disclosed |
| EP-1353934-A1 | NEW INHIBITORS AGAINST GALECTINS | Nilsson, Ulf (SE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002057284-A1 | NEW INHIBITORS AGAINST GALECTINS | NILSSON ULF (SE) | 2002-07-25 | — | — | WO | disclosed |