Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.59 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.55 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367396 | 0.91 | KIF11 (0.67) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4371762 | 0.91 | KIF11 (0.58) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4363480 | 0.90 | KIF11 (0.60) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4361632 | 0.90 | KIF11 (0.72) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4374528 | 0.89 | KIF11 (0.58) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4364309 | 0.88 | KIF11 (0.61) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4365685 | 0.87 | KIF11 (0.59) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4368374 | 0.87 | KIF11 (0.59) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4367439 | 0.86 | KIF11 (0.70) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 | |
| SCHEMBL4373129 | 0.85 | KIF11 (0.63) | KIF11KIF23MAP1LC3BCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166595-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2007-01-23 | — | — | US | disclosed |