SCHEMBL5397

SCHEMBL5397

[CH2]NC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3468035 0.92
Acetic Acid Methyl Ester SCHEMBL9773825 0.70 ALDH1A1 (0.83)
Acetic Acid Methyl Ester SCHEMBL551844 0.70
Ethylene SCHEMBL28608631 0.70
Acetic Acid Methyl Ester SCHEMBL2044980 0.70
Diacetamide SCHEMBL28998044 0.70
Diacetamide SCHEMBL97089 0.67
Acetohydroxamic Acid SCHEMBL14492 0.67
SCHEMBL20411614 0.67
SCHEMBL4397 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15251 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221772-A Mutant with optimized mu-conotoxin structure and application thereof 中国海洋大学 2024-06-21 CN claimed
EP-4380998-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF Research Foundation Of The City University Of New York (US) 2024-06-12 EP claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
EP-3778576-B1 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME HANLIM PHARMACEUTICAL CO LTD (KR) 2024-04-17 EP claimed
US-20240109875-A1 NOVEL METHOD FOR SYNTHESIZING NCA COMPOUNDS ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (ENSCM) (FR) 2024-04-04 US claimed
US-20240101549-A1 N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES ASTRAZENECA AB (SE) 2024-03-28 US claimed
US-11939404-B2 Method for producing cyclized peptide having intramolecular S-S bond AJINOMOTO CO., INC. (JP) 2024-03-26 US claimed
WO-2024031970-A1 COMPOUND WITH ANTI-TUMOR ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国海洋大学 2024-02-15 WO claimed
CN-114276411-B Solid phase synthesis method of cyclic peptide compound containing trithioether bond 北京大学深圳研究生院 2024-02-09 CN claimed
CN-117447548-A Method for modifying cysteine in protein polypeptide by adopting acetamidomethyl 南京农业大学 2024-01-26 CN claimed
US-4105603-A INSULIN AND GLUCAGON SECRETION INHIBITORS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1978-08-08 US claimed
US-4086423-A CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND MERCK & CO., INC. (US) 1978-04-25 US claimed
US-4081433-A D-Nle4 -somatostatin and analogues thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1978-03-28 US claimed
US-4061608-A POLYPEPTIDE, INHIBIT SECRETION OF GROWTH HORMONE AMERICAN HOME PRODUCTS CORPORATION (US) 1977-12-06 US claimed
US-4012345-A POLYPEPTIDES WHICH INHIBIT SECRETION OF GROWTH HORMONE SOMATOTROPIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-15 US claimed
US-4011207-A Des-(Ala1, Gly2,Lys4 -Srif, Des-(Ala1, Gly2, Lys4)-D-Trp8 -Srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-08 US claimed
US-3998795-A (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-21 US claimed
US-3997517-A PEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US claimed
US-3960828-A Catalytic hydrogenolysis of protected sulfur containing peptides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1976-06-01 US claimed
US-3933784-A Des-(ser13)-srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US claimed