SCHEMBL539875

SCHEMBL539875

O=C(O)C1Cc2ccc(O)cc2CN1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.46
EGLN1 Q9GZT9 1/20 0.46
OPRK1 P41145 3/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL539874 1.00 KCNH2 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL29584516 1.00 KCNH2 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL29589035 1.00 KCNH2 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL1280052 1.00 KCNH2 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL29588998 1.00 KCNH2 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
Hydrochloric Acid SCHEMBL7980093 0.98 KCNH2 (0.45) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL546303 0.93 EGLN1 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL7943555 0.93 EGLN1 (0.46) KCNH2EGLN1OPRK1OPRM1OPRD1
Hydrochloric Acid SCHEMBL3998414 0.92 EGLN1 (0.44) KCNH2EGLN1OPRK1OPRM1OPRD1
SCHEMBL20369603 0.85 SCN3A (0.48) KCNH2OPRK1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
WO-2025100520-A1 PEPTIDE, PEPTIDE COMPLEX, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR CELL CULTURE, AND COMPOSITION FOR MEDICAL USE, DIAGNOSTIC USE, OR RESEARCH USE ペプチドリーム株式会社 2025-05-15 WO claimed
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 US claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN claimed
EP-4313159-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY Feldan Bio Inc. (CA) 2024-02-07 EP claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 US claimed
CN-116615205-A Peptide-based transduction of non-anionic polynucleotide analogs for modulation of gene expression 费尔丹生物公司 2023-08-18 CN claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 CN claimed
WO-2022204806-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2022-10-06 WO claimed
US-20220204561-A1 PEPTIDE-BASED NON-PROTEINACEOUS CARGO DELIVERY FELDAN BIO INC. (CA) 2022-06-30 US claimed
CN-114008210-A Peptide-based non-protein cargo delivery 费尔丹生物公司 2022-02-01 CN claimed
WO-2008077194-A1 RECEPTOR AGONISTS XENOME LTD (AU) 2008-07-03 WO claimed
EP-0652897-A4 PEPTIDE INHIBITORS OF SELECTIN BINDING. CENTOCOR INC (US) 1995-09-20 EP claimed
EP-0652897-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR INC. (US) 1995-05-17 EP claimed
WO-1993024527-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR, INC. (US) 1993-12-09 WO claimed
EP-0320785-A2 Peptides influencing the activity of the hypophysis of mammalians HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-21 EP claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US disclosed
WO-1993024527-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR, INC. (US) 1993-12-09 WO disclosed
EP-0320785-A2 Peptides influencing the activity of the hypophysis of mammalians HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 KCNH2 4814/4885EGLN1 4480/4885OPRK1 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.