Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.59 |
| ▸ | PLG | P00747 | 11/20 | 0.59 |
| ▸ | F10 | P00742 | 8/20 | 0.59 |
| ▸ | F2 | P00734 | 7/20 | 0.59 |
| ▸ | PLAT | P00750 | 6/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.59 |
| ▸ | HPN | P05981 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395912 | 0.92 | PLAU (0.49) | PLAUPLGF10F2PLAT | |
| Acetic Acid SCHEMBL6061859 | 0.88 | PLAU (0.46) | PLAUPLGF10F2PLAT | |
| SCHEMBL5394696 | 0.83 | PLAU (0.68) | PLAUPLGF10F2PLAT | |
| SCHEMBL30746755 | 0.80 | PLAU (0.67) | PLAUPLGF10F2PLAT | |
| Acetic Acid SCHEMBL6061722 | 0.79 | PLAU (0.63) | PLAUPLGF10F2PRSS1 | |
| SCHEMBL6530669 | 0.79 | HDAC6 (0.40) | PLAUPLGF10F2PLAT | |
| SCHEMBL5399385 | 0.79 | PLAU (0.54) | PLAUPLGF10F2PLAT | |
| SCHEMBL6530664 | 0.78 | HDAC6 (0.40) | PLAUPLGF10F2PLAT | |
| SCHEMBL13167159 | 0.75 | PLAU (0.71) | PLAUPLGF10F2PLAT | |
| Acetic Acid SCHEMBL6508267 | 0.75 | PLAU (0.50) | PLAUPLGF10F2PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509176-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1682518-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2005040132-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-05-06 | — | — | WO | claimed |