Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 8/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530669 | 0.92 | HDAC6 (0.40) | HDAC6PDE5AHDAC1HDAC2HPSE | |
| SCHEMBL6511656 | 0.88 | AMY1A (0.42) | HDAC6HPSEAMY1AF2F10 | |
| SCHEMBL5395912 | 0.86 | PLAU (0.49) | F2F10PLGPLAUPLAT | |
| SCHEMBL6505100 | 0.83 | HDAC6 (0.41) | HDAC6HDAC1HDAC2PLGPLAU | |
| Acetic Acid SCHEMBL6061859 | 0.82 | PLAU (0.46) | F2F10PLGPLAUPLAT | |
| SCHEMBL6511666 | 0.81 | HDAC6 (0.42) | HDAC6HPSEAMY1AF2F10 | |
| SCHEMBL6510688 | 0.81 | HDAC6 (0.42) | HDAC6HDAC1HDAC2PLAUPRSS1 | |
| SCHEMBL6505174 | 0.79 | HDAC6 (0.46) | HDAC6HPSEAMY1AF2F10 | |
| SCHEMBL5399415 | 0.78 | PLAU (0.59) | F2F10PLGPLAUPLAT | |
| SCHEMBL6505106 | 0.75 | CHEK2 (0.42) | HDAC6HDAC1HDAC2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | claimed |
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | BOYKIN DAVID W (US) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148646-A1 | Dicationic triaryl analogs as anti-protozoan agents | DDT, DDC, DARS1 | HDAC6 466/4885PDE5A 2675/4885HDAC1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.