Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | HBB | P68871 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964750 | 0.85 | TSHR (0.46) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL5379557 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL2971767 | 0.76 | CYP1A2 (0.38) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL27870175 | 0.74 | ESR2 (0.41) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL6650645 | 0.74 | MYC (0.41) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL20598295 | 0.71 | IKBKB (0.49) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL813887 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL4269721 | 0.71 | PDK2 (0.39) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL7084153 | 0.70 | CYP1A2 (0.44) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 | |
| SCHEMBL28247760 | 0.69 | CYP1A2 (0.47) | ALDH1A1HSD17B10HPGDCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166684-B2 | Transition metal compound, catalyst for olefin polymerization and method for producing polyolefin | JAPAN POLYETHYLENE CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20060167196-A1 | Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin | JAPAN POLYETHYLENE CORPORATION (JP) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167196-A1 | Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin | PCLAF, ZKSCAN2, POF1B | ALDH1A1 2910/4885HSD17B10 2089/4885HPGD 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.