⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13512602 | 0.79 | — | — | |
| SCHEMBL8763473 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL7872197 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL9323168 | 0.78 | — | — | |
| SCHEMBL17117091 | 0.78 | — | — | |
| SCHEMBL9913337 | 0.77 | — | — | |
| SCHEMBL5702380 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL18245458 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL1394370 | 0.74 | — | — | |
| SCHEMBL5450077 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051268-A1 | METHOD FOR PREPARING ISOCYANATE BY MEANS OF GAS-PHASE SOLVENT-FREE METHOD | MOJIA (SHANGHAI) BIOTECH CO., LTD. (CN) | 2025-02-13 | — | — | US | claimed |
| WO-2024007204-A1 | METHOD FOR PREPARING ISOCYANATE BY COMBINING SUPERCRITICAL PHOSGENATION METHOD WITH PIPING METHOD | 摩珈(上海)生物科技有限公司 | 2024-01-11 | — | — | WO | claimed |
| CN-113105364-B | Method and system for producing isocyanates | 广安摩珈生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| WO-2023108620-A1 | METHOD FOR PREPARING ISOCYANATE BY MEANS OF GAS-PHASE SOLVENT-FREE METHOD | 摩珈(上海)生物科技有限公司 | 2023-06-22 | — | — | WO | claimed |
| CN-115108942-A | Method for preparing isocyanate by supercritical phosgenation reaction | 摩珈(上海)生物科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-115093348-A | Method for preparing isocyanate by pipeline phosgene method | 摩珈(上海)生物科技有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-115043758-A | Method for preparing isocyanate by combining supercritical phosgenation method with pipelining method | 摩珈(上海)生物科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| WO-2025040153-A1 | METHOD FOR PREPARING ISOCYANATE AND DEVICE | 摩珈(上海)生物科技有限公司 | 2025-02-27 | — | — | WO | disclosed |
| US-20250051268-A1 | METHOD FOR PREPARING ISOCYANATE BY MEANS OF GAS-PHASE SOLVENT-FREE METHOD | MOJIA (SHANGHAI) BIOTECH CO., LTD. (CN) | 2025-02-13 | — | — | US | disclosed |
| WO-2024007204-A1 | METHOD FOR PREPARING ISOCYANATE BY COMBINING SUPERCRITICAL PHOSGENATION METHOD WITH PIPING METHOD | 摩珈(上海)生物科技有限公司 | 2024-01-11 | — | — | WO | disclosed |
| CN-115108942-B | Method for preparing isocyanate by supercritical phosgenation reaction | 摩珈(上海)生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115043758-B | Method for preparing isocyanate by combining supercritical phosgenation method and pipelining method | 摩珈(上海)生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115093348-B | Method for preparing isocyanate by pipeline phosgene method | 摩珈(上海)生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-4855504-A | Process for producing higher molecular weight amino compounds having reduced monomeric amine content | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0178525-A2 | Process for the preparation of high molecular weight amino compounds with lowered amine monomer content as well as their use | BAYER AG (DE) | 1986-04-23 | — | — | EP | disclosed |
| EP-0025907-B1 | HALOGENATED TERTIARY ALKYL ISOCYANATES AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4344891-A | Halogenated tertiary alkyl isocyanates and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0025907-A1 | Halogenated tertiary alkyl isocyanates and process for their preparation | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |
| US-4224238-A | Process for preparing tertiary alkyl isocyanates | SHOWA DENKO K.K. (JP) | 1980-09-23 | — | — | US | disclosed |
| US-4156738-A | Ureidonitriles useful as antihypertensives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-29 | — | — | US | disclosed |