SCHEMBL8763473

SCHEMBL8763473

CC(C)(CC(C)(C)N=C=O)N=C=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1394370 0.88
SCHEMBL17664914 0.86
SCHEMBL15358708 0.84
SCHEMBL13512602 0.82
SCHEMBL22685113 0.82
SCHEMBL7872197 0.81 TSHR (0.32) TSHRCASP1
SCHEMBL17117091 0.80
SCHEMBL10272394 0.80
SCHEMBL15308264 0.80
SCHEMBL539979 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3486238-B1 POLYFUNCTIONAL OXETANE DERIVATIVES FOR PREPARING CATIONIC PHOTOCURABLE COMPOSITIONS CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-06-16 EP disclosed
WO-2020099567-A1 ENCAPSULATED BIOCIDES LONZA LTD (CH) 2020-05-22 WO disclosed
US-9782486-B2 Albumin conjugated temperature and pH-sensitive multi-block copolymer, a method of preparation thereof and drug delivery system using the same Research & Business Foundation Sungkyunkwan University (KR) 2017-10-10 US disclosed
EP-2322504-B9 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2017-09-06 EP disclosed
US-9572892-B2 Polymer conjugate for delivery of a bioactive agent POLYACTIVA PTY LTD (AU) 2017-02-21 US disclosed
WO-2016178971-A1 TRIGGERABLE SHAPE MEMORY INDUCTION DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-11-10 WO disclosed
EP-2322504-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2016-09-28 EP disclosed
US-20160199541-A1 Bioelastomers and Applications Thereof THE PENN STATE RESEARCH FOUNDATION (US) 2016-07-14 US disclosed
US-20160070210-A1 ENDLESS BELT, TRANSFER UNIT, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2016-03-10 US disclosed
US-20160000929-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2016-01-07 US disclosed
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed
EP-0025907-B1 HALOGENATED TERTIARY ALKYL ISOCYANATES AND PROCESS FOR THEIR PREPARATION BASF Aktiengesellschaft (DE) 1984-06-20 EP disclosed
US-4344891-A Halogenated tertiary alkyl isocyanates and their preparation BASF AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
EP-0025907-A1 Halogenated tertiary alkyl isocyanates and process for their preparation BASF Aktiengesellschaft (DE) 1981-04-01 EP disclosed
US-4224238-A Process for preparing tertiary alkyl isocyanates SHOWA DENKO K.K. (JP) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000929-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT PTGIS, PTGIR, PGF TSHR 2489/4885CASP1 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.