Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.71 |
| ▸ | MMP2 | P08253 | 12/20 | 0.70 |
| ▸ | MMP9 | P14780 | 12/20 | 0.70 |
| ▸ | MMP8 | P22894 | 12/20 | 0.70 |
| ▸ | MMP14 | P50281 | 12/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MMP11 | P24347 | 2/20 | 0.67 |
| ▸ | MMP7 | P09237 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556658 | 0.98 | NMBR (0.74) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL5381814 | 0.94 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL29472048 | 0.94 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL1711383 | 0.94 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL31326046 | 0.92 | NMBR (0.74) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL5379426 | 0.91 | MMP2 (0.66) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL11765479 | 0.90 | NMBR (0.71) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL16617130 | 0.90 | NMBR (0.71) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL5380023 | 0.90 | NMBR (0.71) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL14027229 | 0.90 | NMBR (0.71) | NMBRMMP2MMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163671-B2 | Long-term stabilized formulations | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20030092622-A1 | Preparation stabilized over long time | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1260230-A1 | PREPARATIONS STABILIZED OVER LONG TIME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-11-27 | — | — | EP | disclosed |