Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527964 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1ATMHTTXDH | |
| SCHEMBL10737493 | 0.94 | KDM4E (0.47) | KDM4EALDH1A1ATMHTTXDH | |
| SCHEMBL9702416 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1ATMHTT | |
| SCHEMBL6299778 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| Quinoline SCHEMBL27304819 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL11500095 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL11487649 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1ATMHTTL3MBTL1 | |
| SCHEMBL18380643 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1ATMHTTHPGD | |
| SCHEMBL29616919 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1ATMHTTHPGD | |
| SCHEMBL8491858 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1ATMHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003066565-A1 | DEUTERATED BIPHENYL DERIVATIVES | TURICUM DRUG DEVELOPMENT AG (CH) | 2003-08-14 | — | — | WO | claimed |
| EP-0627433-B1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | EISAI CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| JP-5194302-A | — | — | None | — | — | JP | disclosed |
| WO-2024159724-A1 | O-BIPHENYL OXAZOLINE COMPOUND AND SYNTHESIS METHOD THEREFOR | 科莱博(江苏)科技股份有限公司 | 2024-08-08 | — | — | WO | disclosed |
| US-11987928-B2 | Fabric coating compositions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2024-05-21 | — | — | US | disclosed |
| US-11939455-B2 | Polyolefin formulation with poly(2-alkyl-2-oxazoline) | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-03-26 | — | — | US | disclosed |
| CN-112166151-B | Polyolefin formulation with poly (2-alkyl-2-oxazolines) | 陶氏环球技术有限责任公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20220136170-A1 | FABRIC COATING COMPOSITIONS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2022-05-05 | — | — | US | disclosed |
| CN-114269982-A | Fabric coating composition | 惠普发展公司，有限责任合伙企业 | 2022-04-01 | — | — | CN | disclosed |
| EP-3908690-A1 | FABRIC COATING COMPOSITIONS | Hewlett-Packard Development Company, L.P. (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20210221983-A1 | POLYOLEFIN FORMULATION WITH POLY(2-ALKYL-2-OXAZOLINE) | DOW GLOBAL TECHNOLOGIES LLC | 2021-07-22 | — | — | US | disclosed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| US-4578522-A | CHEMICAL INTERMEDIATES FOR BLOOD LIPID CONTROLLING COMPOUNDS | BURROUGHS WELLCOME CO. | 1986-03-25 | — | — | US | disclosed |
| US-4567289-A | ANTICHOLESTEROL ANTILIPEMIC | MERCK & CO., INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0168902-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4515792-A | Tetracyclic heterocycles and antidepressant compositions thereof | CIBA-GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4459422-A | Substituted pyranone inhibitors of cholesterol synthesis | MERCK & CO., INC. (US) | 1984-07-10 | — | — | US | disclosed |
| US-4375475-A | ANTICHOLESTEROL AGENTS | MERCK & CO., INC. (US) | 1983-03-01 | — | — | US | disclosed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | disclosed |
| EP-0024348-A1 | Substituted 6-Phenethyl-and phenylethenyl-3,4,5,6-tetrahydro-4-hydroxytetraydropyran-2-ones in the4-R trans stereoisomeric forms and the corresponding dihydroxy acids, process for preparing and pharmaceutical composition comprising them | MERCK & CO. INC. (US) | 1981-03-04 | — | — | EP | disclosed |