Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033542 | 0.88 | ESR1 (0.57) | MAPTESR1KMOKMT2AMARS1 | |
| SCHEMBL4034670 | 0.83 | ESR1 (0.43) | MAPTESR1KMOMARS1 | |
| SCHEMBL4025361 | 0.77 | ESR1 (0.62) | MAPTESR1ALDH1A1LMNAHTT | |
| SCHEMBL4203517 | 0.77 | ESR1 (0.64) | ESR1KMOMARS1 | |
| SCHEMBL15631868 | 0.77 | MAPT (0.83) | MAPTKDM4EHSD17B10TSHRKMO | |
| SCHEMBL5412777 | 0.75 | KMT2A (0.48) | MAPTESR1KDM4EHSD17B10TSHR | |
| SCHEMBL5409043 | 0.75 | PTGER1 (0.48) | MAPTESR1KDM4EHSD17B10TSHR | |
| SCHEMBL4032520 | 0.74 | ESR1 (0.60) | MAPTESR1KDM4EHSD17B10TSHR | |
| SCHEMBL11832928 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10TSHRALDH1A1 | |
| SCHEMBL4030028 | 0.73 | ESR1 (0.47) | MAPTESR1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241791-B2 | Substituted 4-(indazol-3-yl)phenols | WYETH (US) | 2007-07-10 | — | — | US | disclosed |