SCHEMBL5401035

SCHEMBL5401035

C[Si](C)([O])CCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
SLC22A6 Q4U2R8 2/20 0.50
TSHR P16473 5/20 0.48
NFKB1 P19838 1/20 0.48
PMP22 Q01453 1/20 0.48
AKR1B1 P15121 1/20 0.46
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 7/20 0.44
PPARD Q03181 7/20 0.44
PPARA Q07869 7/20 0.44
HDAC11 Q96DB2 5/20 0.44
PTPN1 P18031 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FABP4 P15090 2/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18237528 0.81 LMNA (0.53) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL2786329 0.81 LMNA (0.53) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL512941 0.80 TSHR (0.48) LMNASLC22A6TSHRNFKB1PMP22
Hydrochloric Acid SCHEMBL11151061 0.79 LMNA (0.50) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL5403973 0.79 LMNA (0.50) LMNASLC22A6TSHRNFKB1PMP22
Hydrochloric Acid SCHEMBL7534254 0.78 TSHR (0.46) LMNASLC22A6TSHRNFKB1PMP22
Hydrochloric Acid SCHEMBL5368847 0.78 TSHR (0.46) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL23322447 0.77 LMNA (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL7251783 0.77 LMNA (0.48) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL18227175 0.77 LMNA (0.48) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157543-B2 Block polyorganosiloxane block organomer polymers and release agents EASTMAN KODAK COMPANY (US) 2007-01-02 US disclosed
US-7084202-B2 Molecular complexes and release agents EASTMAN KODAK COMPANY (US) 2006-08-01 US disclosed
US-20050182206-A1 Block polyorganosiloxane block organomer polymers and release agents KODAK PHILIPPINES LTD. 2005-08-18 US disclosed
US-6894137-B2 Block polyorganosiloxane block organomer polymers and release agents EASMAN KODAK COMPANY (US) 2005-05-17 US disclosed
US-20030232945-A1 Molecular complexes and release agents FAR EAST DEVELOPMENT LTD. 2003-12-18 US disclosed
US-20030232948-A1 Block polyorganosiloxane block organomer polymers and release agents BANK OF AMERICA, N.A., AS AGENT 2003-12-18 US disclosed
WO-1992008758-A1 SILICONE SURFACE-MODIFIED AMMONIUM POLYPHOSPHATE PPG INDUSTRIES, INC. (US) 1992-05-29 WO disclosed