Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523705 | 0.86 | CNR1 (0.43) | NPSR1CNR1CNR2PTGS2CYP3A4 | |
| SCHEMBL542182 | 0.86 | CYP3A4 (0.46) | CYP2D6CYP2C9NPSR1CNR1CNR2 | |
| SCHEMBL27613126 | 0.78 | PTGS2 (0.43) | NPSR1CNR1CNR2PTGS2CYP3A4 | |
| Bicarbonate SCHEMBL11439022 | 0.78 | PTPN1 (0.47) | CYP2C9CNR1CNR2CYP3A4PTPN1 | |
| SCHEMBL29171861 | 0.78 | NPSR1 (0.38) | CYP2D6CYP2C9NPSR1CYP1A2CYP2C19 | |
| SCHEMBL31571441 | 0.77 | CNR1 (0.34) | CYP2D6CYP2C9NPSR1CYP1A2CYP2C19 | |
| SCHEMBL13323514 | 0.77 | CNR1 (0.37) | NPSR1CNR1CNR2PTGS2CYP3A4 | |
| SCHEMBL5182611 | 0.77 | CNR1 (0.37) | NPSR1CNR1CNR2PTGS2CYP3A4 | |
| SCHEMBL29171973 | 0.77 | NPSR1 (0.40) | CYP2D6CYP2C9NPSR1CYP1A2CYP2C19 | |
| SCHEMBL29171938 | 0.75 | CYP1A2 (0.33) | CYP2D6CYP2C9NPSR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585588-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Pharmavan Co., Ltd. (CN) | 2025-07-16 | — | — | EP | disclosed |
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024051354-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州沪云新药研发股份有限公司 | 2024-03-14 | — | — | WO | disclosed |
| US-7255900-B2 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | disclosed |
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | CHRM1, AFF1, H1-0 | CYP2D6 1133/4885CYP2C9 1649/4885NPSR1 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.