SCHEMBL5401484

SCHEMBL5401484

CCCn1ncc(N)c1NC(C)C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
SYK P43405 1/20 0.31
KAT2B Q92831 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
USP2 O75604 1/20 0.31
RAB9A P51151 1/20 0.31
DRD4 P21917 2/20 0.31
DRD2 P14416 1/20 0.31
BCDIN3D Q7Z5W3 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5402337 0.86 BCDIN3D (0.36) BCDIN3D
SCHEMBL5446737 0.84 ADORA2A (0.30)
SCHEMBL5403246 0.79 POLB (0.35) POLBCYP2C19RAB9ALMNA
SCHEMBL5432824 0.79 TNK2 (0.30)
SCHEMBL5441226 0.79 LMNA (0.34) LMNA
SCHEMBL5431674 0.78 CSNK2A1 (0.30)
SCHEMBL14357558 0.78 POLB (0.34) POLB
SCHEMBL5410039 0.77 KAT2B (0.42) KAT2BBCDIN3D
SCHEMBL5405131 0.76 PIK3CD (0.30)
SCHEMBL14357635 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed