Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279605 | 0.95 | HDAC8 (0.53) | HDAC8PTPN1 | |
| SCHEMBL4860126 | 0.95 | HDAC8 (0.53) | HDAC8PTPN1 | |
| SCHEMBL19460386 | 0.86 | PTPN1 (0.48) | HDAC8PTPN1AGTR2 | |
| SCHEMBL17573069 | 0.86 | PTPN1 (0.48) | HDAC8PTPN1AGTR2 | |
| SCHEMBL546157 | 0.86 | ESR2 (0.56) | HDAC8PTPN1AGTR2ACE | |
| SCHEMBL18793348 | 0.83 | PTPN1 (0.68) | HDAC8PTPN1 | |
| SCHEMBL20720251 | 0.83 | PTPN1 (0.68) | HDAC8PTPN1 | |
| SCHEMBL29676960 | 0.83 | PTPN1 (0.68) | HDAC8PTPN1 | |
| SCHEMBL66871 | 0.83 | ACE (0.59) | HDAC8PTPN1ACE | |
| SCHEMBL14067913 | 0.83 | ACE (0.59) | HDAC8PTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |