Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707284 | 1.00 | ACE (0.59) | ACEPOLBTDP1L3MBTL1HDAC8 | |
| SCHEMBL29401053 | 1.00 | ACE (0.59) | ACEPOLBTDP1L3MBTL1HDAC8 | |
| SCHEMBL66872 | 1.00 | ACE (0.59) | ACEPOLBTDP1L3MBTL1HDAC8 | |
| SCHEMBL14067913 | 1.00 | ACE (0.59) | ACEPOLBTDP1L3MBTL1HDAC8 | |
| SCHEMBL2080858 | 1.00 | ACE (0.59) | ACEPOLBTDP1L3MBTL1HDAC8 | |
| SCHEMBL6240970 | 0.87 | PTPN1 (0.48) | ACEHDAC8PTPN1 | |
| SCHEMBL1791198 | 0.87 | UCHL1 (0.48) | ACEPOLBTDP1 | |
| SCHEMBL26748805 | 0.87 | ACE (0.57) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL21490343 | 0.86 | PTPN1 (0.65) | HDAC8PTPN1 | |
| SCHEMBL29443079 | 0.86 | PTPN1 (0.65) | HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024511-A | Novel coronavirus-resistant peptidomimetic compound and preparation method thereof | 烟台大学 | 2023-11-10 | — | — | CN | claimed |
| CN-103450338-B | The Thymopentin that heterocyclic carboxylic acid is modified, it prepares, antitumor action and application | 首都医科大学 | 2016-08-24 | — | — | CN | claimed |
| CN-103304687-B | The preparations and applicatio of-6-(3 ' S-tetrahydroisoquinoline-3 '-formamido group)-6-deoxidation-beta-schardinger dextrin-entirely | Capital Medical University (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-103450344-B | Tetrahydroisoquinoline-3-carboxylic acid modify LARGD seven peptide, its synthesis, antithrombotic acitivity and application | Capital Medical University (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-103450340-B | The antineoplastic oligopeptide that heterocyclic carboxylic acid is modified, its synthesis, antitumor action and application | Capital Medical University (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-103450342-B | Tetrahydroisoquinoline-3-carboxylic acid modify PARGD seven peptide, its synthesis, antithrombotic acitivity and application | Capital Medical University (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-103450343-B | Tetrahydroisoquinoline-3-carboxylic acid modify TARGD seven peptide, its synthesis, antithrombotic acitivity and application | Capital Medical University (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-103450343-A | Tetrahydroisoquinolinyl-3-carboxylic acid modified TARGD heptapeptides, and synthesis, antithrombotic activity and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103450340-A | Heterocyclic carboxylic acid-modified anti-tumor oligopeptides and their synthesis, anti-tumor effects and application | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103450344-A | Tetrahydroisoquinolinyl-3-carboxylic acid modified LARGD heptapeptides, and synthesis, antithrombotic activity and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103450338-A | Heterocyclic carboxylic acid-modified thymopentins and their preparation method, anti-tumor effect and use | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103450342-A | Tetrahydroisoquinolinyl-3-carboxylic acid modified PARGD heptapeptides, and synthesis, antithrombotic activity and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103304687-A | Preparation of full-6-(3'S-tetrahydroisoquinolin-3'-formylamino)-6-deoxy-beta-cyclodextrin and application | UNIV CAPITAL MEDICAL SCIENCES | 2013-09-18 | — | — | CN | claimed |
| CN-101899084-B | (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid kyrine conjugate, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-09-05 | — | — | CN | claimed |
| CN-101899084-A | (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid kyrine conjugate, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2010-12-01 | — | — | CN | claimed |
| CN-101190895-B | N-[(3S)-1,2,3,4-tetrahydroisoquinolino-3-formacyl]amino acid, preparation method and application thereof | CAPITAL UNIVERSITY OF MEDICAL SCIENCES | 2010-05-26 | — | — | CN | claimed |
| CN-101190895-A | N-[(3S)-1,2,3,4-tetrahydroisoquinolino-3-formacyl]amino acid, preparation method and application thereof | UNIV CAPITAL MEDICAL SCIENCES (CN) | 2008-06-04 | — | — | CN | claimed |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PEPTIDREAM INC (JP) | 2026-01-15 | — | — | US | disclosed |
| WO-1993001174-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE AS ANTI-VIRAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| US-4965250-A | TETRAPEPTIDE; IMMUNE SYSTEM ACTIVATION | ADIR ET CIE (FR) | 1990-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | NSUN3, BCAT1, SLC43A1 | ACE 1944/4885POLB 948/4885TDP1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.