Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404342 | 0.90 | PDE1A (0.38) | PDE1APDE1BPDE1CSLC16A1 | |
| SCHEMBL5411056 | 0.88 | — | — | |
| SCHEMBL5408105 | 0.87 | SLC16A1 (0.36) | SLC16A1 | |
| SCHEMBL5415082 | 0.86 | SLC16A1 (0.36) | PDE1APDE1BPDE1CSLC16A1 | |
| SCHEMBL5413292 | 0.85 | SLC16A1 (0.33) | PDE1APDE1BPDE1CSLC16A1 | |
| SCHEMBL5402641 | 0.84 | — | — | |
| SCHEMBL5399340 | 0.81 | PDE5A (0.37) | PDE1APDE1BPDE1CSLC16A1 | |
| SCHEMBL5405559 | 0.80 | CMA1 (0.37) | SLC16A1 | |
| SCHEMBL5398847 | 0.80 | CMA1 (0.35) | SLC16A1 | |
| SCHEMBL5402846 | 0.80 | MAPK14 (0.37) | PDE1APDE1BPDE1CSLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |