Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414603 | 0.86 | F10 (0.51) | F10KLKB1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5398796 | 0.83 | KMT2A (0.51) | F10KLKB1KMT2ARAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5399635 | 0.82 | KMT2A (0.50) | F10KLKB1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5393256 | 0.81 | MAPT (0.63) | F10KLKB1KMT2AALDH1A1MAPT | |
| SCHEMBL9979767 | 0.79 | F10 (0.75) | F10KLKB1 | |
| SCHEMBL9940053 | 0.78 | F10 (0.49) | F10KLKB1KMT2ARAB9AALDH1A1 | |
| SCHEMBL3335278 | 0.69 | F10 (0.70) | F10KLKB1RAB9ANPC1 | |
| SCHEMBL4180936 | 0.68 | KMT2A (0.54) | F10KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2780086 | 0.67 | SLC18A3 (0.67) | KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2780091 | 0.67 | SLC18A3 (0.67) | KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | claimed |
| US-7307074-B2 | Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration | ASTELLAS PHARMA INC. (JP) | 2007-12-11 | — | — | US | claimed |