Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414603 | 0.90 | F10 (0.51) | F10KLKB1MAPTKMT2AALDH1A1 | |
| SCHEMBL9979803 | 0.79 | F10 (0.73) | F10KLKB1 | |
| SCHEMBL5393256 | 0.79 | MAPT (0.63) | F10KLKB1MAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5403614 | 0.78 | F10 (0.72) | F10KLKB1 | |
| SCHEMBL5403408 | 0.78 | F10 (0.51) | F10KLKB1MAPTKMT2AALDH1A1 | |
| SCHEMBL5398796 | 0.72 | KMT2A (0.51) | F10KLKB1MAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5399635 | 0.71 | KMT2A (0.50) | F10KLKB1MAPTKMT2AALDH1A1 | |
| SCHEMBL6235992 | 0.68 | HDAC3 (0.54) | — | |
| SCHEMBL9979731 | 0.67 | F10 (0.73) | F10KLKB1MAPTKMT2AL3MBTL1 | |
| SCHEMBL6132372 | 0.67 | HDAC3 (0.53) | KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | claimed |