Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540111 | 0.90 | SLC6A5 (0.71) | SLC6A5TRPV1CNR1ALDH1A1HPGD | |
| SCHEMBL5520639 | 0.90 | SLC6A5 (0.71) | SLC6A5TRPV1CNR1ALDH1A1HPGD | |
| SCHEMBL5520632 | 0.90 | SLC6A5 (0.71) | SLC6A5TRPV1CNR1ALDH1A1HPGD | |
| SCHEMBL3505712 | 0.90 | SLC6A5 (0.71) | SLC6A5TRPV1CNR1ALDH1A1HPGD | |
| SCHEMBL13114491 | 0.85 | LPAR1 (0.56) | SLC6A5TRPV1CNR1ALDH1A1HPGD | |
| SCHEMBL24022038 | 0.85 | CNR1 (0.67) | TRPV1CNR1ALDH1A1HPGDCNR2 | |
| SCHEMBL29360245 | 0.85 | CNR1 (0.67) | TRPV1CNR1ALDH1A1HPGDCNR2 | |
| SCHEMBL4397932 | 0.85 | CNR1 (0.67) | TRPV1CNR1ALDH1A1HPGDCNR2 | |
| SCHEMBL4397935 | 0.85 | CNR1 (0.67) | TRPV1CNR1ALDH1A1HPGDCNR2 | |
| SCHEMBL13114485 | 0.84 | LPAR1 (0.55) | SLC6A5TRPV1CNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414322-A2 | POLYAMINE DERIVATIVES | Egen, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |