Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682491 | 0.79 | KCNN4 (0.46) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL2583837 | 0.77 | KCNN4 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL5740730 | 0.76 | TAAR1 (0.50) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL6678725 | 0.75 | TAAR1 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL2121739 | 0.74 | TAAR1 (0.48) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL2208547 | 0.73 | CYP2C19 (0.41) | KCNN4TAAR1ALDH1A1CYP2C19HIF1A | |
| SCHEMBL2239057 | 0.72 | TAAR1 (0.46) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL20752446 | 0.71 | TAAR1 (0.41) | KCNN4TAAR1MAPK1ALDH1A1TP53 | |
| SCHEMBL10544554 | 0.71 | TAAR1 (0.46) | KCNN4TAAR1MAPK1CYP2C19HIF1A | |
| SCHEMBL1059898 | 0.70 | KCNN4 (0.48) | KCNN4TAAR1MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413693-A1 | SUBSTITUTED AZOANTHRACENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | TransTech Pharma, Inc (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114824-A1 | SUBSTITUTED AZOANTHRACENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | TRANSTECH PHARMA INC (US) | 2010-10-07 | — | — | WO | disclosed |