Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339642 | 0.80 | KCNN4 (0.41) | KCNN4TAAR1MAPK1KIF11TSHR | |
| Iodide SCHEMBL28547565 | 0.78 | KCNN4 (0.40) | KCNN4TAAR1MAPK1KIF11TSHR | |
| SCHEMBL20752446 | 0.78 | TAAR1 (0.41) | KCNN4TAAR1MAPK1ALDH1A1TP53 | |
| SCHEMBL1971090 | 0.78 | KCNN4 (0.48) | KCNN4TAAR1MAPK1KIF11TSHR | |
| SCHEMBL540402 | 0.77 | KCNN4 (0.43) | KCNN4TAAR1MAPK1KIF11TSHR | |
| SCHEMBL6678725 | 0.77 | TAAR1 (0.44) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL6682491 | 0.76 | KCNN4 (0.46) | KCNN4TAAR1MAPK1TSHRALDH1A1 | |
| SCHEMBL14743401 | 0.75 | KIF11 (0.37) | MAPK1KIF11TSHRALDH1A1CYP2C19 | |
| SCHEMBL2208547 | 0.75 | CYP2C19 (0.41) | KCNN4TAAR1ALDH1A1CYP2C19HIF1A | |
| SCHEMBL21577161 | 0.73 | SIGMAR1 (0.40) | MAPK1KIF11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137331-A2 | 4-FLUORO-4-ARYLPIPERDIN-1-YL DERIVATIVES AS MU OPIOID FUNCTION MODERATORS | KINENTIA BIOSCIENCES LLC (US) | 2011-11-03 | — | — | WO | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1996005828-A1 | PYRROLIDINYL DI-CARBOXYLIC ACID DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-02-29 | — | — | WO | disclosed |