Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL29408372 | 0.95 | — | — | |
| Benzimidazole SCHEMBL29358377 | 0.95 | — | — | |
| Benzimidazole SCHEMBL461969 | 0.95 | SMN1; SMN2 (0.50) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 | |
| Benzimidazole SCHEMBL6009 | 0.95 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.95 | SMN1; SMN2 (0.50) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 | |
| Benzimidazole SCHEMBL2334176 | 0.93 | PRKCI (0.50) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 | |
| Benzimidazole SCHEMBL23673327 | 0.93 | SMN1; SMN2 (0.48) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 | |
| Benzimidazole SCHEMBL21046391 | 0.93 | — | — | |
| Benzimidazole SCHEMBL4883891 | 0.93 | KDM4E (0.48) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 | |
| Benzimidazole SCHEMBL22551123 | 0.93 | SMN1; SMN2 (0.48) | PRKCIKDM4EMAPTRAD52SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244847-B2 | Benzimidazole compounds | ISIS PHARMACEUTICALS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| WO-2004047769-A2 | BENZIMIDAZOLES AND ANALOGS THEREOF AS ANTIBACTERIALS | ISIS PHARMACEUTICALS, INC. (US) | 2004-06-10 | — | — | WO | disclosed |
| US-20030187258-A1 | Novel benzimidazole compounds | US GOVERNMENT - SECRETARY FOR THE ARMY | 2003-10-02 | — | — | US | disclosed |
| WO-2003066622-A1 | NOVEL BENZIMIDAZOLE COMPOUNDS | ISIS, PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187258-A1 | Novel benzimidazole compounds | BRD4, BRI3BP, BRD3 | PRKCI 2292/4885KDM4E 835/4885MAPT 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.