Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930788 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL21694311 | 0.85 | CD44 (0.48) | ALDH1A1CD44MAPTCYP3A4LMNA | |
| SCHEMBL23493021 | 0.85 | CD44 (0.48) | ALDH1A1CD44MAPTKDM4ETDP1 | |
| SCHEMBL11703860 | 0.84 | MCHR1 (0.50) | ALDH1A1CD44MAPTMEN1KMT2A | |
| SCHEMBL21694326 | 0.83 | CD44 (0.46) | ALDH1A1CD44MAPTMEN1KMT2A | |
| SCHEMBL23493037 | 0.83 | CD44 (0.46) | ALDH1A1CD44MAPTMEN1KMT2A | |
| SCHEMBL11800324 | 0.82 | CYP1A2 (0.59) | CD44MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL23493027 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CD44MAPTMEN1KMT2A | |
| SCHEMBL23493036 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CD44MAPTMEN1KMT2A | |
| SCHEMBL23493024 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CD44MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136061-A | SIK inhibitors and methods of use thereof | 索尔特戈公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20230265099-A1 | SIK INHIBITORS AND METHODS OF USE THEREOF | SOLTEGO, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| EP-4213851-A1 | SIK INHIBITORS AND METHODS OF USE THEREOF | Soltego, Inc. (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |
| WO-2022061312-A1 | SIK INHIBITORS AND METHODS OF USE THEREOF | SOLTEGO, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
| CN-111718332-B | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111718332-A | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2020-09-29 | — | — | CN | disclosed |
| WO-2020187292-A1 | 2-SUBSTITUTED PYRAZOLEAMINO-4-SUBSTITUTED AMINO-5-PYRIMIDINE FORMAMIDE COMPOUND, COMPOSITION AND USE THEREOF | 北京赛特明强医药科技有限公司 | 2020-09-24 | — | — | WO | disclosed |
| WO-2020032090-A1 | EPOXY COMPOUND, EPOXY RESIN, EPOXY RESIN COMPOSITION, CURED RESIN PRODUCT, PREPREG, FIBER-REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHOD FOR THESE | 帝人株式会社 | 2020-02-13 | — | — | WO | disclosed |
| EP-2808320-B1 | Triphenylamine derivative, method for manufacturing the same, and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2020-02-12 | — | — | EP | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4141718-A | ANTIGROWTH AGENTS FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4012222-A | Herbicidal compositions containing dioxolane substituted anilids and method therefor | VELSICOL CHEMICAL CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3983174-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3948950-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3946045-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |
| US-3942972-A | Dioxolane substituted α-haloanilides as herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3940259-A | Dioxane substituted-α-haloanilides as herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265099-A1 | SIK INHIBITORS AND METHODS OF USE THEREOF | SIK2, SIK1, SIK3 | ALDH1A1 4493/4885CD44 2227/4885MAPT 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.