Profluralin

Profluralin

SCHEMBL54045

CCCN(CC1CC1)c1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.76
CYP3A4 P08684 3/20 0.76
MAPK1 P28482 2/20 0.76
TSHR P16473 2/20 0.76
MAPT P10636 4/20 0.62
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
CNR2 P34972 3/20 0.43
ALDH1A1 P00352 3/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HIF1A Q16665 1/20 0.42
TXNRD1 Q16881 1/20 0.42
TXNRD3 Q86VQ6 1/20 0.42
TXNRD2 Q9NNW7 1/20 0.42
POLB P06746 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
AR P10275 1/20 0.41
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Profluralin SCHEMBL8535232 1.00 TDP1 (0.76) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11494026 0.90 MAPT (0.64) TDP1CYP3A4MAPK1TSHRMAPT
Trifluralin SCHEMBL21994 0.87 TDP1 (1.00) TDP1CYP3A4MAPK1TSHRMAPT
Trifluralin SCHEMBL8409474 0.87 TDP1 (1.00) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11187583 0.84 TDP1 (0.70) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11204357 0.84 TDP1 (0.89) TDP1CYP3A4MAPK1TSHRMAPT
Profluralin SCHEMBL9676043 0.82 TDP1 (0.52) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11202092 0.82 CYP3A4 (0.89) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11185104 0.82 TDP1 (0.50) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11428095 0.81 CYP3A4 (0.49) TDP1CYP3A4MAPK1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5883 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20250057161-A1 USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM ADAMA MAKHTESHIM LTD. (IL) 2025-02-20 US claimed
EP-4472412-A1 HERBICIDAL COMBINATIONS UPL Corporation Limited (MU) 2024-12-11 EP claimed
US-20240130368-A1 HERBICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-04-25 US claimed
EP-4316244-A1 HERBICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-02-07 EP claimed
CN-116867373-A Herbicidal composition 日本曹达株式会社 2023-10-10 CN claimed
US-20230284618-A1 HERBICIDAL COMBINATIONS UPL CORPORATION LTD (MU) 2023-09-14 US claimed
EP-0070219-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIOPYRIMIDINE DERIVATIVES AND 2,6-DINITROANILINE DERIVATIVES, AND METHOD OF TREATING CROPS WITH SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1984-10-24 EP claimed
US-4415355-A PREEMERGENCE HERBICIDES; CRYSTAL GROWTH INHIBITORS BASF WYANDOTTE CORPORATION (US) 1983-11-15 US claimed
US-4382813-A Encapsulation by entrapment within starch adduct matrix THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1983-05-10 US claimed
EP-0070130-A1 Improvement in or relating to benzoylphenyl urea derivatives ELI LILLY AND COMPANY (US) 1983-01-19 EP claimed
EP-0070219-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and 2,6-dinitroaniline derivatives, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP claimed
EP-0051161-A1 Encapsulation by entrapment within starch adduct matrix AGRO-CAP INTERNATIONAL, INC. (US) 1982-05-12 EP claimed
US-4226789-A Removal of nitrosamines from denitroanilines by treatment with HCl ELI LILLY AND COMPANY (US) 1980-10-07 US claimed
US-4185035-A REMOVAL OF NITROSAMINES WITH PHOSPHORUS HALIDES ELI LILLY AND COMPANY (US) 1980-01-22 US claimed
US-4127610-A REMOVAL OF NITROSAMINES ELI LILLY AND COMPANY (US) 1978-11-28 US claimed
US-4077795-A 2,4-DINITROANILINE DERIVATIVES UNION CARBIDE CORPORATION (US) 1978-03-07 US claimed