Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399225 | 0.85 | ALOX15 (0.32) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL1048785 | 0.77 | KDM4E (0.32) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6902805 | 0.75 | CYP2C19 (0.34) | MAPTALDH1A1MAPK1 | |
| SCHEMBL5399792 | 0.73 | ALOX15 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| Hydrochloric Acid SCHEMBL5399224 | 0.73 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| Hydrochloric Acid SCHEMBL5397360 | 0.73 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL5397368 | 0.72 | MAPT (0.31) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL17386892 | 0.72 | — | — | |
| SCHEMBL7036428 | 0.71 | MAPT (0.38) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL6287702 | 0.71 | KDM4E (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220695-B2 | Supported activator | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-22 | — | — | US | claimed |